3D Printed Tubular Scaffolds with Massively Tailorable Mechanical Behavior

Melt electrowriting (MEW) is a promising additive manufacturing technique for tissue scaffold biofabrication. Successful application of MEW scaffolds requires strictly controlled mechanical behavior. This geometry be optimized to match native properties while simultaneously supporting cell attachment and proliferation. The objective this work investigate how geometric can exploited massively tailor the behavior tubular crosshatch scaffolds. An experimentally validated finite element (FE) model developed 441 geometries are investigated under tension, compression, bending, radial loading. A range pore areas (4–150 mm2) angles (11°–134°) investigated. It found that tunable through control these simple parameters. Across ranges investigated, stiffness varies by factor 294× 204× 231× 124× Further, it discussed parameters tuned different biomimetic material applications. provides critical insights into design achieve an important tool in development engineered constructs.